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    Advanced Cardiovascular Life Support Algorithms

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    Adult Cardiac Arrest Algorithm

    Last reviewed October 19, 2026 · Based on ILCOR and AHA guidelines 2025-2030

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    ACLS Adult Cardiac Arrest Algorithm flowchart

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    Adult Cardiac Arrest Algorithm: Step by Step

    1. Start CPR

      Then check the rhythm. Shockable (VF/pVT): go to step 2. Nonshockable (asystole/PEA): go to step 9.

      • Begin high-quality chest compressions
      • Provide bag-mask ventilation with oxygen
      • Connect the patient to a monitor/defibrillator
    2. VF/pVT

      The rhythm is shockable.

    3. Deliver shock

    4. Resume CPR for 2 minutes

      Then check the rhythm. Shockable: go to step 5. Not shockable: go to step 13.

      • Establish IV/IO access
    5. Deliver shock

    6. Resume CPR for 2 minutes

      Then check the rhythm. Shockable: go to step 7. Not shockable: go to step 13.

      • Administer epinephrine every 3-5 minutes
      • Consider advanced airway placement and waveform capnography
    7. Deliver shock

    8. Resume CPR for 2 minutes

      Then return to the rhythm check before step 5.

      • Administer amiodarone or lidocaine
      • Identify and treat reversible causes (H’s and T’s)
    9. Asystole/PEA

      The rhythm is not shockable.

    10. Give epinephrine immediately

    11. Resume CPR for 2 minutes

      Then check the rhythm. Shockable: go to step 5. Not shockable: go to step 12.

      • Establish IV/IO access
      • Administer epinephrine every 3-5 minutes
      • Consider advanced airway placement and waveform capnography
    12. Resume CPR for 2 minutes

      Then check the rhythm. Shockable: go to step 5. Not shockable: go to step 13.

      • Identify and treat reversible causes (H’s and T’s)
    13. Assess for ROSC

      • If there are no signs of ROSC, go to step 11
      • If ROSC is present, go to post-cardiac arrest care
      • Evaluate whether further resuscitation is appropriate

    High-quality CPR

    • Depth: compress at least 2 inches (5 cm); avoid depths over 2.4 inches (6 cm)
    • Rate: deliver 100-120 compressions/min, allowing full chest recoil after each compression
    • Minimize chest compression interruptions
    • Switch the rescuer performing compressions every 2 minutes (or earlier if tired)
    • Avoid excessive ventilation: do not give breaths too frequently or use excessive tidal volumes
    • Without an advanced airway: use a ratio of 30 compressions to 2 breaths (30:2)
    • With an advanced airway: provide 1 breath every 6 seconds (10 breaths/min) without pausing chest compressions
    • Use continuous waveform capnography. If ETCO₂ is low or falling, reassess CPR quality

    Advanced airway management

    • Airway options: endotracheal intubation (ETI) or a supraglottic airway (SGA)
    • Confirm correct ET tube placement and monitor its position using continuous waveform capnography or capnometry

    Defibrillation energy settings

    • Biphasic, first shock: select the energy recommended by the manufacturer (e.g., 120-200 J). If the recommendation is unknown, use the device’s maximum energy setting
    • Biphasic, subsequent shocks: maintain the previous energy level. Consider increasing it according to the manufacturer’s guidance
    • Monophasic: use 360 J for each shock

    Medication dosing

    • Epinephrine IV/IO: give 1 mg and repeat every 3-5 minutes
    • Amiodarone IV/IO: first dose 300 mg bolus; second dose 150 mg
    • Lidocaine IV/IO: first dose 1-1.5 mg/kg; second dose 0.5-0.75 mg/kg

    Reversible causes (H’s and T’s)

    • H’s: hypovolemia, hypoxia, hydrogen ion (acidosis), hypo- or hyperkalemia, hypothermia
    • T’s: tension pneumothorax, tamponade (cardiac), toxins, thrombosis (pulmonary), thrombosis (coronary)

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